Oncoinfection
Assess whether genetic profiles and proliferative indexes differ between pre-malignant lesions (ex. STIC lesions) and their next state of progression
If not, what accounts for progression?
If tumor suppressor disruption permits constitutive dsRNA response signaling, are cells 'conditioned' akin to a constitutive antiviral injection towards a cellular state suited to evade the immune system and expand locally and distally?
If not, what accounts for progression?
If tumor suppressor disruption permits constitutive dsRNA response signaling, are cells 'conditioned' akin to a constitutive antiviral injection towards a cellular state suited to evade the immune system and expand locally and distally?